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compound 1 against various bacteria organism enoyl acp reductase mic  (ATCC)


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    Structured Review

    ATCC compound 1 against various bacteria organism enoyl acp reductase mic
    Compound 1 Against Various Bacteria Organism Enoyl Acp Reductase Mic, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 17828 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/compound+1+against+various+bacteria+organism+enoyl+acp+reductase+mic/MIC/pm30501172-206-355-385
    Average 99 stars, based on 17828 article reviews
    compound 1 against various bacteria organism enoyl acp reductase mic - by Bioz Stars, 2026-09
    99/100 stars

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    Inhibition:

    Article Title: The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection.
    Article Snippet: .. Genus/Organisma FabI FabK Repressor Bacteriodes + ± FabT Page 28 of 38 ACS Paragon Plus Environment ACS Infectious Diseases 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 aNot shown: FabV is primarily found in Vibrio species, FabL in Bacillus species. bYeast-like Fatty Acid synthase cKnown to use endogenous fatty acids to bypass FASII Bifidobacteriumb Not Found C. difficile + FapR Enterobacterium + ± FapR E. faecalis + + FabT E. faecium + FabT Faecalibacterium + FabT Lactobacillus + ± FabT Peptostreptococcus + FabT Propionibacterium + FabT Staphylococcus + FapR Streptococcusc + FabT Page 29 of 38 ACS Paragon Plus Environment ACS Infectious Diseases 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Table 2: Inhibition concentrations of C. difficile CD630 by different fatty acids Fatty acid Abbreviation MIC (μM) Acetic acid C2:0 >512 Butyric acid C4:0 >512 Octanoic acid C8:0 >512 Decanoic acid C10:0 >512 Dodecanoic acid C12:0 32 Myristic acid C14:0 64 Palmitic acid C16:0 >512 Stearic acid C18:0 >512 Oleic acid C18:1Δ9 128 Linoleic acid C18:2Δ9,12 64 Linolenic acid C18:3Δ9,12,15 32 Arachidonic acid C20:4Δ5,10,11,14 32 Page 30 of 38 ACS Paragon Plus Environment ACS Infectious Diseases 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Table 3: Minimum inhibitory concentrations (MICs)a for compound 1 against various bacteria Organism Enoyl-ACP reductase MIC (M) - Palmitic acid + Palmitic acid C. difficile CD630 FabK 16 16 C. difficile R20291 FabK 8 2 S. pyogenes ATCC 19615 FabK <0.0625 4 C. perfringens HM310 FabV >64 >64 B. ovatus HM222 FabI & FabK >64 >64 L. reuteri LTH 5448 FabI >64 >64 S. aureus Newman FabI >64 >64 aVancomycin’s MIC against test strains ranged from 0.25-1 M. With exception of S. pyogenes MICs were done with addition of verapamil (100 g/mL). ..

    Bacteria:

    Article Title: The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection.
    Article Snippet: .. Genus/Organisma FabI FabK Repressor Bacteriodes + ± FabT Page 28 of 38 ACS Paragon Plus Environment ACS Infectious Diseases 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 aNot shown: FabV is primarily found in Vibrio species, FabL in Bacillus species. bYeast-like Fatty Acid synthase cKnown to use endogenous fatty acids to bypass FASII Bifidobacteriumb Not Found C. difficile + FapR Enterobacterium + ± FapR E. faecalis + + FabT E. faecium + FabT Faecalibacterium + FabT Lactobacillus + ± FabT Peptostreptococcus + FabT Propionibacterium + FabT Staphylococcus + FapR Streptococcusc + FabT Page 29 of 38 ACS Paragon Plus Environment ACS Infectious Diseases 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Table 2: Inhibition concentrations of C. difficile CD630 by different fatty acids Fatty acid Abbreviation MIC (μM) Acetic acid C2:0 >512 Butyric acid C4:0 >512 Octanoic acid C8:0 >512 Decanoic acid C10:0 >512 Dodecanoic acid C12:0 32 Myristic acid C14:0 64 Palmitic acid C16:0 >512 Stearic acid C18:0 >512 Oleic acid C18:1Δ9 128 Linoleic acid C18:2Δ9,12 64 Linolenic acid C18:3Δ9,12,15 32 Arachidonic acid C20:4Δ5,10,11,14 32 Page 30 of 38 ACS Paragon Plus Environment ACS Infectious Diseases 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Table 3: Minimum inhibitory concentrations (MICs)a for compound 1 against various bacteria Organism Enoyl-ACP reductase MIC (M) - Palmitic acid + Palmitic acid C. difficile CD630 FabK 16 16 C. difficile R20291 FabK 8 2 S. pyogenes ATCC 19615 FabK <0.0625 4 C. perfringens HM310 FabV >64 >64 B. ovatus HM222 FabI & FabK >64 >64 L. reuteri LTH 5448 FabI >64 >64 S. aureus Newman FabI >64 >64 aVancomycin’s MIC against test strains ranged from 0.25-1 M. With exception of S. pyogenes MICs were done with addition of verapamil (100 g/mL). ..



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    ATCC compound 1 against various bacteria organism enoyl acp reductase mic
    Compound 1 Against Various Bacteria Organism Enoyl Acp Reductase Mic, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/compound+1+against+various+bacteria+organism+enoyl+acp+reductase+mic/MIC/pm30501172-206-355-385
    Average 99 stars, based on 1 article reviews
    compound 1 against various bacteria organism enoyl acp reductase mic - by Bioz Stars, 2026-09
    99/100 stars
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